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K2VITAL - Your Key to Optimal Bone Health

Vitamin K2 acts as a co-factor necessary for activation of osteocalcin, which facilitates binding of calcium to bones.

When activated, osteocalcin enables calcium to be incorporated into the bone matrix (hydroxyapatite) and thereby build new bone.

Bone Health - The Importance of vitamin K2, vitamin D3 and calcium

Bones are a living substance, constantly renewed
The skeleton is built up by bone (hydroxyapatite) supplemented by ligaments, tendons, muscles and cartilage.  Calcium is an important building block in the bone matrix. There are constantly bone building processes ongoing and the entire skeleton is replaced every seven years. Build-up cells (osteoblasts) and break-down cells (osteoclasts) regulate the strength of bones. When breakdown cell activity dominates, the skeleton becomes fragile and this may result in development of osteoporosis.

Post-menopausal women are particularly at risk for development of brittle bones, leading to fractures. Worldwide, lifetime risk of osteoporotic fractures in women and men is 30-50% and 15-30%, respectively (International Osteoporosis Foundation).

The importance of combining vitamin K2, vitamin D3 and calcium
The most widely used supplements to support bone health are calcium and vitamin D3. Vitamin D3 increases the intestinal uptake of calcium; the most important bone-building mineral. Vitamin D3 also induces the synthesis of  osteocalcin, which is responsible  for incorporation of calcium into the bone matrix. Osteocalcin however, is dependent on activation by vitamin K before it can react with calcium and build bone. Individuals with low vitamin K2 intake have a large fraction of non-activated osteocalcin, resulting in reduced capacity for calcium binding.

To secure the optimal bone building process, vitamin K2, vitamin D3 and calcium must work in combination.

To learn more about K2VITAL®'s Bone Health benefits, please contact us.